A huge emergency response has turned out at the site of a serious crash which involved a car and a float carrying multiple horses in Ellenbrook this morning.

The horse float was being towed by a grey Ford Ranger on The Promenade when it collided with a red MG about 9.15am, flipping the float on its side.

Witnesses reported one horse escaped and was caught at a nearby shopping centre and another had to be sedated before being extricated from the float.

A 36-year-old male passenger of the MG was taken to Royal Perth Hospital. It is understood the driver of the car sustained seatbelt injuries.

WA Police could not provide further details of the incident at this stage.

Anyone with information or who witnessed the vehicles in Ellenbrook should contact Crime Stoppers online or by calling 1800 333 000.

Dash-cam or mobile phone vision relating to this crash can be uploaded directly to investigators via this link.

More to come.